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Adrenic Acid

Name: Adrenic Acid
Brand: TargetMol
SKU: T19180
Price: 393 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19180Cas No. 28874-58-0

Alias cis-7,10,13,16-Docosatetraenoic acid

Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a very-long-chain fatty acid present in blood and human myelin tissue.

Adrenic Acid

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Purity: 98.42%

Catalog No. T19180Alias cis-7,10,13,16-Docosatetraenoic acidCas No. 28874-58-0

Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a very-long-chain fatty acid present in blood and human myelin tissue.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	-	In Stock
5 mg	$109	-	In Stock
10 mg	$159	-	In Stock
25 mg	$265	-	In Stock
50 mg	$393	-	In Stock
100 mg	Inquiry	-	In Stock
1 mL x 10 mM (in DMSO)	$230	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.42%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a very-long-chain fatty acid present in blood and human myelin tissue.
In vitro	The hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). The hepatic and plasma levels of Adrenic Acid exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid.
Synonyms	cis-7,10,13,16-Docosatetraenoic acid

Chemical Properties

Molecular Weight	332.52
Formula	C₂₂H₃₆O₂
Cas No.	28874-58-0
Smiles	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O
Relative Density.	0.9220 g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 260 mg/mL (781.91 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+ 90% PBS: ≥ 0.3 mg/mL

10% DMSO+ 90% Corn oil: ≥ 0.3 mg/mL

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0073 mL	15.0367 mL	30.0734 mL	150.3669 mL
5 mM	0.6015 mL	3.0073 mL	6.0147 mL	30.0734 mL
10 mM	0.3007 mL	1.5037 mL	3.0073 mL	15.0367 mL
20 mM	0.1504 mL	0.7518 mL	1.5037 mL	7.5183 mL
50 mM	0.0601 mL	0.3007 mL	0.6015 mL	3.0073 mL
100 mM	0.0301 mL	0.1504 mL	0.3007 mL	1.5037 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc